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UTILIZING DR. FRANK HOLLY'S UNPRECEDENTED KNOWLEDGE OF THE HUMAN TEAR FILM and OCULAR SURFACE
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Aqueous Pharma was founded by Joe Echols, to focus on innovative therapy for dry eye syndrome on a global basis. Assets include the 3 original artificial tear products & the patented ophthalmic solution preservative developed by Dr. Frank J. Holly, and Aqueous has developed a new tear product, FRESHKOTE, reviewed on page 2 of this site. BREAKING NEWS: APL-106 DEVELOPED AS NEW TEAR STIMULATION /ENHANCEMENT PRODUCT. PATENT FILED IN THE USA. SEE: WWW.ARTIFICIALTEARS.NET for more details
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Effective Artificial Tears Should Have: Low Viscosity - High Oncotic Pressure (~65mmHg) except for mild dry eye
- Appropriate Synergistic Blending of Polymers
- Added Nutrients or other components depending on etiology of Dry Eye type
- Effective and Non-Irritating Preservative for multidose or non-preserved for unit of use
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Dry eye is the most frequently diagnosed ocular disorder worldwide. Artificial tear products are front line therapy for this condition with this market showing growth of over 20% annually. Other tear products do not address healing of the ocular surface and only provide a temporary relief of symptoms; thereby providing the motivation for Aqueous Pharma to develop uniquely effective formulations.
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All 4 tear formulations are the first to enhance wettability of ocular surface cells. NUTRATEAR, containing Vitamin B12, is for mild dry eye/overuse of computers. DAKRINA has been found effective in mucin-deficient dry eye due to its polymer-solubilized vitamin A; bio-available to the ocular surface and DAKRINA is the only tear clinically shown to increase goblet cell density in Sjogren's syndrome patients in a study at Duke University by Dr. Gary Foulks. All formulations are in compliance with the FDA Ophthalmic Monograph. FreshKote, Dakrina & Dwelle have been cleared for OTC Marketing in the UK by the MHRA (British Regulatory Authority). FRESHKOTE (code: APL-105) was approved in all European Union Countries in November 2006 via CE Mark. All 4 tears are preserved with the highly effective but yet totally non-irritating preservative, polyquaternium-42 (also known as polixetonium). NutraTear, Dakrina & Dwelle are Dr. Holly's original (core) products. More information on FreshKote is on page 2 of this site and at www.freshkote.com . FRESHKOTE is exclusively marketed in the USA by FOCUS Laboratories of North Little Rock, Arkansas - ph: 1-501-753-6006.
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